![]() ![]() ![]() ![]() Use with caution in patients with cardiovascular disease, hypertension, endocrine disorders, osteoporosis and myxedema.Dosage must be carefully titrated to maintain optimal levels to treat hypothyroidism and prevent hyperthyroidism Avoid undertreatment or overtreatment may cause several adverse effects.Do not use levothyroxine to treat male or female infertility, unless it is associated with hypothyroidism.Do not use in patients with uncorrected adrenal insufficiency thyroid hormones may precipitate an acute adrenal crisis.Use with caution in the treatment of goiter or nodules in patients with normal thyroid function.Avoid use in patients with goiter or thyroid nodules with low TSH levels.Do not use oral levothyroxine to treat myxedema coma, use intravenous formulations.Do not use in patients with suppressed TSH and elevated thyroid hormone levels in the blood ( thyrotoxicosis).Do not use in patients with hypersensitivity to levothyroxine or any of its ingredients.Do not use in patients with an acute heart attack ( myocardial infarction).In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction larger doses may produce serious or even life-threatening signs of toxicity, especially when used with drugs that cause loss of appetite ( anorexia) Do not use levothyroxine for weight loss, either alone or with other therapeutic agents.Organ preservation in brain-dead organ donors (Orphan designation).As an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.To prevent and treat thyroid enlargement (goiter), nodules and inflammation in patients with normal thyroid function (euthyroid).Myxedema coma, a rare medical emergency with loss of brain function due to severe long-standing hypothyroidism. ![]() Subclinical hypothyroidism (normal thyroid hormone levels, but mildly elevated TSH).Tertiary hypothyroidism (hypothalamus disorder).Secondary hypothyroidism (pituitary disorder).Primary hypothyroidism (thyroid disorder).Hypothyroidism, acquired or congenital, from any cause including:.Levothyroxine is used in the following conditions: Impairment in the normal functioning of any part of this axis can cause hypothyroidism. TRH stimulates the pituitary gland to secrete thyrotropin-stimulating hormone (TSH), which in turn stimulates the thyroid gland to produce thyroid hormones T3 and T4. Based on feedback from blood levels of thyroid hormones, the hypothalamus region in the brain secretes thyrotropin-releasing hormone (TRH). Thyroid hormone secretion is regulated by the hypothalamus-pituitary-thyroid axis. Hypothyroidism may be caused by thyroid disorders, due to radiation for neck and head cancers, certain medications or thyroid surgery/removal. Hypothyroidism leads to several metabolic disorders, weight gain, infertility, bone disorders, and heart problems. Thyroid hormones have many important functions in maintaining mental and physical health in adults, and normal physical growth and mental development in children. Levothyroxine medication replaces or supplements deficiency in natural thyroxine. Levothyroxine is prescribed to treat hypothyroidism, a condition in which the thyroid gland produces insufficient thyroid hormones. The thyroid gland produces thyroid hormones using iodine absorbed from dietary intake. Levothyroxine is a synthetic form of thyroid hormone produced by the human thyroid gland, a butterfly-shaped organ located at the base of the neck. What is levothyroxine, and what is it used for? ![]()
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